Exercise Physiology
Hamidreza Nayeri khoob
Abstract
Galectin-3 is a member of the galectin family and galectin-3 used as a diagnostic or prognostic biomarker for certain types of heart disease, kidney disease and cancer. Intensive exercise increases the levels of this protein, but the effect of regular exercise to ameliorate galectin-3 responses to high-intensity ...
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Galectin-3 is a member of the galectin family and galectin-3 used as a diagnostic or prognostic biomarker for certain types of heart disease, kidney disease and cancer. Intensive exercise increases the levels of this protein, but the effect of regular exercise to ameliorate galectin-3 responses to high-intensity exercise is not well known. The present study was done to examine the effect of regular resistance training on galectin-3 responses to a bout of heavy resistance training. Eleven young men (age: 26.6±1.5 years old) volunteered to participate in this quasi study. One reparation maximum (1-RM) was measured and the subjects performed a heavy resistance exercise trial consisted of eight exercises (chest press, triceps extension, latissimus pull down, shoulder press, arm curls, leg extension, leg curls, and squat) of 8 repetitions with 3 sets at 80% of 1RM. Thereafter, all the subjects performed 3 sets of the same resistance training with 65-80% 1RM, 3 days a week for 8 weeks. 48h after the last session of training, a bout of heavy resistance exercise was done again. Blood samples were taken at baseline and immediately after the heavy resistance exercise trials. The results demonstrated that galectin-3 increases after the first bout of heavy resistance exercise (P<0.05), while galectin-3 concentration reduce after the 8 weeks of regular resistance training and it remain low after the second bout of heavy resistance exercise. Generally, we can conclude that regular resistance exercise is effective to ameliorate galectin-3 responses to a bout of heavy resistance training in young men.
